The first official USS Boxer was a brig constructed and commissioned in 1815, with Lt. John Porter as the first Commanding Officer. That year the Boxer put to sea for the Mediterranean Sea with Mr. Thomas D. Anderson, the American consul to Tunis, emkarked. She delivered her passenger and then served briefly with Commodore William Bainbridge's Mediterranean Squadron before returning to the United States. In 1816, Boxer sailed south for New Orleans. She spent the remainder of her career cruising the waters of the Gulf of Mexico and the West Indies protecting American trade in the area from West Indian pirates. She was lost at sea off Belize, British Honduras, on 25 October 1817, but her crew was saved.
For more detailed history on the first USS Boxer visit the Navy Archive page